Years of American-led investment into AIDS programs has reduced the number of people killed by the disease to the lowest levels seen in more than three decades, and provided life-saving medicines for some of the world's most vulnerable.

But in the last six months, the sudden withdrawal of U.S. money has caused a "systemic shock," U.N. officials warned, adding that if the funding isn't replaced, it could lead to more than 4 million AIDS-related deaths and 6 million more HIV infections by 2029.

Elie Saab, the Lebanese designer long favored on the red carpet, returned to familiar territory on Wednesday, with fall haute couture — and did so unapologetically.

In Paris, fashion insiders gathered among marble columns as models descended a gilded stone staircase to the strains of harpsichord music, setting the tone for a collection steeped in historical romance.

Mireille Rebeiz, Dickinson College

After a 12-day war launched by Israel and joined briefly by the United States, Iran has emerged weakened and vulnerable. And that has massive implications for another country in the region: Lebanon.

Kylian Mbappé has dropped the legal proceedings he started this year against Paris Saint-Germain for moral harassment, a person with knowledge of the situation told the Associated Press.

The Paris prosecutor's office last month said Mbappé accused the club in a legal filing, and opened an investigation. A person close to the France captain said on Tuesday that Mbappé's decision to end that legal procedure was linked to a desire for reconciliation with his former club.

Pope Leo XIV prayed Wednesday for the world to recognize the urgency of the climate crisis and "hear the cry of the poor," as he celebrated the first papal Mass using a new set of prayers and readings inspired by Pope Francis' environmental legacy.

The Mass, in the gardens of the Vatican's new ecological educational center at the papal summer estate in Castel Gandolfo, indicated a strong line of ecological continuity with Francis, who made environmental protection a hallmark of his pontificate.

U.S. President Donald Trump is hosting five West African leaders on Wednesday for a "multilateral lunch" at the White House as the region reels from the impact of U.S. aid cuts.

The leaders of Liberia, Senegal, Gabon, Mauritania and Guinea-Bissau are expected to discuss key areas of cooperation, including economic development, security, infrastructure and democracy, according to a statement from the Liberian presidency. The White House has not provided further details.

Spanish Prime Minister Pedro Sánchez presented anti-corruption measures in response to the mounting corruption cases involving his Socialist Party, and again said he would not step down from office.

Speaking in parliament Wednesday at an extraordinary session about a corruption probe involving a former Socialist Party official, the Spanish leader took responsibility for his poor judgement but repeatedly said he would not step down, calling himself "an honest politician" with "the pride of leading an exemplary party."

World shares mostly climbed on Wednesday, following a choppy trading day on Wall Street as the Trump administration seeks to win more favorable trade deals with nations around the globe.

In early trading, major indexes in Europe were all higher. Germany's DAX added 0.7% to 24,373.05. Britain's FTSE 100 edged 0.1% higher to 8,861.90. France's CAC 40 rose 0.8% to 7,829.04.

President Donald Trump and his advisers promised a lightning round of global trade negotiations with dozens of countries back in April.

White House trade adviser Peter Navarro predicted "90 deals in 90 days.'' Administration officials declared that other countries were desperate to make concessions to avoid the massive import taxes – tariffs -- that Trump was threatening to plaster on their products starting July 9.

It's a bird, it's a plane, it's a … a purple and orange shape-shifting chemical compound?

Writer-director James Gunn's "Superman" was always going to be a strange chemistry of filmmaker and material. Gunn, the mind behind "Guardians of the Galaxy" and "The Suicide Squad," has reliably drifted toward a B-movie superhero realm populated (usually over-populated) with the lesser-known freaks, oddities and grotesquerie of back-issue comics.