Iran's Revolutionary Guards said they struck a center of Mossad, Israel's foreign intelligence service, in Tel Aviv on Tuesday, amid an escalating air war between the two foes.

In a statement aired on state television, the Guards said they "struck the military intelligence centre of the Zionist regime's army, Aman, and the Zionist regime's terrorist operations planning centre, the Mossad, in Tel Aviv", adding it was "currently on fire".

After Israeli strikes landed near the hotel where he was staying in the Iranian province of Qom, Aimal Hussein desperately wanted to return home. But the 55-year-old Afghan businessman couldn't find a way, with Iranian airspace completely shut down.

He fled to Tehran after the strike Sunday, but no taxi would take him to the border as the conflict between Iran and Israel intensified.

U.S. President Donald Trump said Tuesday he was aiming for a "real end" to the conflict between arch-rivals Israel and Iran, and not just a ceasefire.

"I'm not looking for a ceasefire, we're looking at better than a ceasefire," Trump told reporters on board Air Force One before arriving back in the United States from a G7 summit in Canada.

Iran's Foreign Minister and chief nuclear negotiator Abbas Araghchi said Israel's strikes against his country "deal a blow" to diplomacy during a call Monday with his French, British, and German counterparts.

"The Israeli aggression against Iran in the midst of nuclear negotiations with the United States is a blow to diplomacy," Abbas Araghchi said during a call reported by his ministry with French Foreign Minister Jean-Noel Barrot, the United Kingdom's David Lammy, Germany's Johann Wadephul, and the European Union's head of foreign affairs Kaja Kallas.

U.S. President Donald Trump left a G7 summit in Canada a day early on Monday, heading back to the White House as Israel and Iran traded missile fire for a fifth straight day.

Trump's helicopter lifted off from the summit venue in the Canadian Rockies to take him to his plane, shortly after he warned residents to evacuate the Iranian capital Tehran.

TIsrael's strikes on the headquarters of Iran's state television in Tehran killed three people, the broadcaster said on Tuesday, a day after the attack.

"Three of the TV station's employees were killed and others were wounded in the Israeli attack" on Monday, the channel announced, without specifying the number of people hospitalized.

The White House is discussing with Iran the possibility of a meeting this week between U.S. envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi, four sources briefed on the issue told U.S. news portal Axios.

Iran said it destroyed strategic targets in Israel overnight using drones, as intense strikes between the arch-foes raged for a fifth day on Tuesday.

"Various types of destructive drones, equipped with precise destruction and targeting capabilities, destroyed strategic positions of the Zionist regime in Tel Aviv and Haifa," General Kioumars Heidari, commander of the army's ground forces, was quoted as saying by state television.

Israel appeared to be expanding its air campaign on Tehran five days after its surprise attack on Iran's military and nuclear program, as U.S. President Donald Trump posted an ominous message warning residents of the city to evacuate.

“IRAN CAN NOT HAVE A NUCLEAR WEAPON,” Trump wrote Monday night before returning to Washington early from a Group of Seven summit in Canada. “Everyone should immediately evacuate Tehran!” he added.

Gaza's civil defense agency said Israeli forces on Tuesday killed at least 47 people gathered near an aid distribution site in Khan Yunis in the south.

Civil defense spokesman Mahmud Bassal told AFP that at least 47 people were killed and more than 200 wounded as thousands of Palestinians gathered to receive flour at a charity aid center in the morning. "Israeli drones fired at the citizens. Some minutes later, Israeli tanks fired several shells at the citizens, which led to a large number of martyrs and wounded," he said.