Iran said Monday the attacks launched on the Islamic republic during talks about its nuclear program were a "betrayal of diplomacy".

"We and future generations will not forget that the Iranians were in the middle of a diplomatic process with a country that is now at war with us," said foreign ministry spokesman Esmaeil Baqaei.

Sirens wailed across Israel for over 30 minutes on Monday and loud explosions were heard in Jerusalem on Monday, as the military warned of multiple missile barrages launched from arch-foe Iran.

After the extended alert period in several areas of the country, the Israeli military later said civilians could leave shelters.

The United Nations special envoy for Syria denounced Sunday's attack on a church in Damascus that killed at least 20 people as a "heinous crime".

Prime Minister Benjamin Netanyahu said Sunday that his promise to destroy Iran's nuclear facilities had been "fulfilled" following strikes carried out "in perfect coordination" between the Israeli and U.S. militaries.

Iran's Foreign Minister Abbas Araghchi on Sunday condemned US attacks on key nuclear sites as "outrageous" and said his country has a right to defend its sovereignty.

"The events this morning are outrageous and will have everlasting consequences," he posted on X, adding that the attacks were "lawless and criminal" behaviour.

The U.N.'s International Atomic Energy Agency (IAEA) on Sunday said that it had not detected any increase in radiation levels at key nuclear sites in Iran following U.S. air strikes.

The Israeli military said it launched a fresh series of strikes Sunday targeting military targets including missile launchers in western Iran after the United States attacked the country's nuclear sites.

At least 16 people were hurt and at least one impact was reported in central Israel after Iran launched two waves of missiles at the country following the U.S. bombing of its nuclear sites, rescue services and reports said.

U.S. President Donald Trump said U.S. air strikes on Sunday "totally obliterated" Iran's main nuclear sites, as Washington joined Israel's war with Tehran in a flashpoint moment for the Middle East.

In a televised address to the nation from the White House, Trump warned that the United States would go after more targets if Iran did not make peace quickly.

Israel targeted "two centrifuge production sites" at Iran's Isfahan nuclear facility overnight in a second wave of strikes on the location since the start of the war, a military official said on Saturday.