The Israeli military said it launched a fresh series of strikes Sunday targeting military targets including missile launchers in western Iran after the United States attacked the country's nuclear sites.

At least 16 people were hurt and at least one impact was reported in central Israel after Iran launched two waves of missiles at the country following the U.S. bombing of its nuclear sites, rescue services and reports said.

U.S. President Donald Trump said U.S. air strikes on Sunday "totally obliterated" Iran's main nuclear sites, as Washington joined Israel's war with Tehran in a flashpoint moment for the Middle East.

In a televised address to the nation from the White House, Trump warned that the United States would go after more targets if Iran did not make peace quickly.

Israel's military said Saturday its navy hit a Hezbollah "infrastructure site" near the southern Lebanese city of Naqoura, a day after Israel's defense minister warned the Lebanese armed group against entering the Iran-Israel war.

"Overnight, an Israeli Navy vessel struck a Hezbollah 'Radwan Force' terrorist infrastructure site in the area of Naqoura in southern Lebanon," the Israeli army said in a statement.

The Lebanese health ministry said an Israeli strike on south Lebanon's al-Abbasiyeh killed one person, as Israel said it killed a member of Hezbollah.

Israel has continued to carry out near-daily strikes on Lebanon despite a November ceasefire with Hezbollah and an unprecedented bombing campaign it launched on Iran last week.

Israel targeted "two centrifuge production sites" at Iran's Isfahan nuclear facility overnight in a second wave of strikes on the location since the start of the war, a military official said on Saturday.

Israel claimed on Saturday it has already set back Iran's presumed nuclear program by at least two years, a day after U.S. President Donald Trump warned that Tehran has a "maximum" of two weeks to avoid possible American air strikes.

U.S. President Donald Trump said overnight that Iran had a "maximum" of two weeks to avoid possible U.S. air strikes, indicating he could take a decision before the fortnight deadline he set a day earlier.

At least 23 heavy Iranian missiles were fired at Israel on Friday afternoon, causing extensive damage in Tel Aviv and wounding at least 10 in Haifa, two of them seriously, after six missiles managed to penetrate Israel’s air defenses, Iranian and Israeli media reports said.

Video footage showed a missile causing a big explosion in Haifa, with Israel’s Channel 13 saying there are fears of a possible leakage of dangerous material.

Gaza's civil defense agency said Israeli forces killed at least 43 people on Friday, including 26 who had gathered near an aid distribution center, the latest in a string of deadly incidents targeting aid seekers in the Palestinian territory.

"Forty-three martyrs have fallen as a result of the ongoing Israeli bombardment on the Gaza Strip since dawn today, 26 of whom were waiting for humanitarian aid," Mohammad Al-Mughayyir, director of medical supply at the civil defense agency in Gaza, told AFP.