Arsenal and Manchester United face off for the 217th time on Sunday, with the London club bidding to establish an 11-point lead over the champions in the Premier League.
Their rivalry has produced some of the most memorable matches in English football history and here, Agence France Presse Sports selects the pick of those encounters:
Full StoryManchester City manager Manuel Pellegrini will keep "his trust" with goalkeeper Costel Pantilimon for their trip to Sunderland on Sunday.
Pellegrini controversially dropped number one Joe Hart last weekend for their comprehensive win over Norwich after a number of costly errors this season and replaced him with the Romanian.
Full StoryNigerian President Goodluck Jonathan will on Sunday host the country's team who won the FIFA Under-17 World Cup in the United Arab Emirates.
Nigeria beat Mexico 3-0 in Friday's final in Abu Dhabi to win a record fourth U17 World Cup after they previously triumphed in 1985, 1993 and 2007.
Full StoryBastian Schweinsteiger is to undergo another operation on his right ankle, ruling the Germany midfielder out indefinitely.
The 29-year-old Schweinsteiger, who underwent surgery on the troublesome ankle in July, needs another operation after failing to recover as planned from the previous one, Bayern Munich announced on its website on Friday.
Full StorySeven concussions in 18 months ended Shaun Valentine's rugby league playing career, and the lingering effects concerned him so much he decided to donate his brain to a man he's never met and rarely spoken to.
He understands that he'll die without knowing the full impact of those concussions, but hopes his decision will help future generations of athletes.
Full StoryLos Angeles' Steve Blake hit a 3-pointer with 1.3 seconds remaining to lift the Lakers to a 99-98 victory over Houston and ex-teammate Dwight Howard on Thursday.
Also Thursday, Miami held off the Los Angeles Clippers and Denver edged Atlanta.
Full StoryEngland coach Roy Hodgson has recognized Southampton's strong start to the season by calling up three players from the south-coast club for friendlies, including two who have never played for their country.
Striker Jay Rodgriguez has been included in the squad for the first time for the matches against Chile and Germany, having scored four goals for Southampton this season.
Full StoryFormer Brazil and Barcelona midfielder Rivaldo says he is leaving Brazilian second-division club Sao Caetano because of knee pain.
The 41-year-old player made the announcement through his official Twitter account on Thursday, saying he "was not able to recover from pain" in his knee.
Full StoryAfter nearly a year of global travel and dozens of matches, most of Novak Djokovic's rivals are complaining about their mental and physical fatigue. Not the Serb, who thrives in the rigors of a tough autumn finish.
Unbeaten since his loss in the U.S. Open final to Rafael Nadal, Djokovic joined Nadal in the semifinals of the ATP World Tour Finals after overcoming strong resistance from Juan Martin del Potro on Thursday.
Full StoryTottenham, Fiorentina and Red Bull Salzburg made it four group wins out of four in the Europa League on Thursday to qualify for the knockout phase with two games to spare.
Record-signing Erik Lamela scored his first Tottenham goal before winning the penalty that Jermain Defoe converted to clinch a 2-1 victory over Sheriff Tiraspol in Group K.
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